Home Chemistry Heterocyclic Building Blocks Triazoles 2-Phenyl-2H-Benzo[D][1,2,3]Triazole
Substitution Reactions: The phenyl group on the triazole ring can undergo various substitution reactions. For example, you can perform electrophilic aromatic substitution reactions such as nitration, halogenation (e.g., bromination or chlorination), or Friedel-Crafts acylation/alkylation to introduce different substituents onto the phenyl ring.
Reduction Reactions: You can reduce the nitro group (if introduced) or other functional groups on the phenyl ring using reducing agents like hydrogen gas over a metal catalyst (e.g., palladium on carbon), which would lead to the corresponding amine.
Acylation Reactions: You can perform acylation reactions on the nitrogen atom of the triazole ring to introduce acyl groups. For example, reacting it with acyl chlorides or anhydrides in the presence of a base can lead to the formation of amides.
Alkylation Reactions: You can alkylate the nitrogen atom of the triazole ring using alkyl halides or other alkylating agents to introduce alkyl groups.
Hydrogenation: The aromatic ring can undergo catalytic hydrogenation in the presence of a suitable catalyst (e.g., palladium on carbon) to convert it into a saturated cyclohexyl ring.
Oxidation Reactions: You can oxidize any available functional groups to introduce new functionalities. For instance, you can oxidize an alcohol to a ketone or aldehyde.
Cyclization Reactions: Depending on the reagents and conditions, 2-phenyl-2H-benzo[d][1,2,3]triazole may participate in various cyclization reactions to form fused or bridged ring systems.
Heterocyclic Chemistry: The triazole ring itself can participate in various heterocyclic reactions, such as ring opening, ring expansion, or ring closure reactions, depending on the reactants and conditions.
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2,4-Di-tert-butyl-6-(5-chloro-2H-benzo[d][1,2,3]triazol-2-yl)phenol
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2-(2H-Benzo[d][1,2,3]triazol-2-yl)-6-(sec-butyl)-4-(tert-butyl)phenol
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4-(2H-Benzo[d][1,2,3]triazol-2-yl)benzene-1,3-diol
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2-(tert-Butyl)-6-(5-chloro-2H-benzo[d][1,2,3]triazol-2-yl)-4-methylphenol
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2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)phenol
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3-(3-(2H-Benzo[d][1,2,3]triazol-2-yl)-5-(tert-butyl)-4-hydroxyphenyl)propanoic acid
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2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4,6-di-tert-butylphenol
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